HIV acquires a nano-enemy

日期:2019-03-02 03:13:01 作者:花遑怨 阅读:

CARBON nanotubes have been used to smuggle HIV-blocking molecules into human cells. Small interfering RNA molecules (siRNA) had been suggested as an HIV treatment, because they destroy messenger RNA, which is used to make the cell-surface proteins HIV needs to infect immune cells called T-cells. The hard part is getting siRNA into T-cells. Now Hongjie Dai and colleagues at Stanford University in California have attached siRNA to carbon nanotubes, which penetrate T-cell membranes and deposit the siRNA inside the cells. When siRNA-laden nanotubes were added to human T-cells,